MP12 Antidepressant Prescribing Guidance for Adults (over 18) with Moderate to Severe Depression

Medicine management
Issue No

Target Audience

All Clinical Staff CWP
Clinical Staff working within the Commissioning CCGs


This pathway is a whole system approach in that it has been agreed in consultation with the CCGs. The pathway concentrates on the treatment of moderate to severe depression with medication for adults over 18 years (for child and adolescent management refer to the NICE clinical guidelines (September 2005) including comparison of anti-depressants and guidance on stopping and swapping anti-depressants. This pathway should be used in conjunction with the full depression care pathway.


Lead executive
Medical Director, Compliance, Quality and Assurance

Authors details
Deputy Chief Pharmacist - 01244 397380

Policy dates & history

Implementation Date

15 February 2019

Approval Meeting

CWP Medicines Management Group
Central & Eastern Cheshire APC
Wirral Medicines Management Committee
West Cheshire APC


MP12 Issue 6 Antidepressant Prescribing Guidance.pdf

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